Absorption, distribution and excretion of L-DOPS in animals.

The Absorption, Excretion, and Distribution of Penicillin.

Thiouracil. Its Absorption, Distribution, and Excretion.

Absorption, distribution, metabolism, and excretion of ticagrelor in healthy subjects.

Ticagrelor [(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl) cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol)] is a reversibly binding oral P2Y(12) receptor antagonist in development for the prevention of thrombotic events in patients with acute coronary syndromes. The pharmacokinetics, metabolism, and excretion of ticagrelor...

Absorption, distribution, metabolism, and excretion of [C]-dasotraline in humans

Dasotraline is a dopamine and norepinephrine reuptake inhibitor, and the early clinical trials show a slow absorption and long elimination half-life. To investigate the absorption, distribution, metabolism, and excretion of dasotraline in humans, a single dose of [C]-dasotraline was administered to eight healthy male adult volunteers. At 35 days, 90.7% of the dosed radioactivity was recovered i...

The Absorption, Distribution and Excretion of Einalool in the Rat

5 % respectively of the total (whole homogenate) activity; the postmitochondrial (1OOOOg) supernatant contained the whole of the activity. Further, on resuspending the microsomal fraction in the cell sap, all the dimethylnitrosamine demethylase activity was restored. The kinetics of dimethylnitrosamine demethylase were investigated in hepatic 1OOOOg supernatants over a substrate concentration r...